MOXIFLOXACIN HYDROCHELORIDE
Moxifloxacin
CAS: 151096-09-2
Molecular Formula: C21H24FN3O4
MOXIFLOXACIN HYDROCHELORIDE - Names and Identifiers
| Name | Moxifloxacin |
| Synonyms | Avdox CS-83 Moxifloxacin MOXIFLOXACIN MAXIOFFOXACIN Moxifloxacin EP Impurity MOXIFLOXACIN HYDROCHELORIDE Moxifloxacin Hydrochloride 2 (1'S,6'S)-1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihyd (1'S,6'S)-1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (4αS-cis)-1-Cydopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(octahydro-6H-pyrrolo[3,4-b]pyridin-6-y1)-4-oxo-3-quinolinecarboxylic acid 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
| CAS | 151096-09-2 |
| EINECS | 604-773-0 |
| InChI | InChI=1/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1 |
MOXIFLOXACIN HYDROCHELORIDE - Physico-chemical Properties
| Molecular Formula | C21H24FN3O4 |
| Molar Mass | 401.43 |
| Density | 1.408±0.06 g/cm3(Predicted) |
| Melting Point | 203-208 C |
| Boling Point | 636.4±55.0 °C(Predicted) |
| Specific Rotation(α) | 23D -193° |
| Flash Point | 338.7°C |
| Solubility | Acetonitrile (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly) |
| Vapor Presure | 4.56E-17mmHg at 25°C |
| Appearance | Solid |
| Color | Off-White to Light Yellow |
| pKa | 6.43±0.50(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Stability | Hygroscopic |
| Refractive Index | 1.633 |
| In vitro study | The in vitro activities of Moxifloxacin and Amoxicillin are compared by time-kill curve and inhibition of intracellular growth experiments by using a model of bone marrow-derived mouse macrophages infected by L. monocytogenes EGDe. Moxifloxacin acts much more rapidly, beginning to exert its effects in the first 3 h and achieving complete broth sterilization within 24 h of incubation. Moxifloxacin appears to have a protective effect against macrophage lysis, as many cells are still viable after 24 h of incubation. |
MOXIFLOXACIN HYDROCHELORIDE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R40 - Limited evidence of a carcinogenic effect |
| Safety Description | 36/37 - Wear suitable protective clothing and gloves. |
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View History
MOXIFLOXACIN HYDROCHELORIDE
B-PHENYLETHYLAMINE HCL
坚牢蓝K盐
叔丁基乙酸
5-Nitro-3-(trifluoromethyl)pyridin-2-ol, 5-Nitro-3-(trifluoromethyl)pyridin-2(1H)-one
N-[(1S)-1-氰基-2-甲基丙基]-氨基甲酸叔丁酯
PEG-5 椰油基甲基铵甲基硫酸盐
5-{[(2-fluorobenzyl)thio]methyl}-2-furoic acid
B-PHENYLETHYLAMINE HCL
坚牢蓝K盐
叔丁基乙酸
5-Nitro-3-(trifluoromethyl)pyridin-2-ol, 5-Nitro-3-(trifluoromethyl)pyridin-2(1H)-one
N-[(1S)-1-氰基-2-甲基丙基]-氨基甲酸叔丁酯
PEG-5 椰油基甲基铵甲基硫酸盐
5-{[(2-fluorobenzyl)thio]methyl}-2-furoic acid